Management of paracetamol overdose Paediatrics and Child Health Acquired pyroglutamic acidosis due to long term dicloxacillin and paracetamol use BMJ Case Reports g glutamyl cycle. Depletion of glutathione by acetaminophen leads to Download Scientific Diagram Paracetamol Induced Hepatotoxicity , Overdose NAPQI formation Glutathione depletion Liver cell necrosis. Early N acetylcysteine (NAC) can save the liver., #Pharmacology #mbbs #Hepatotoxicity File:Paracetamol metabolism.svg Wikimedia Commons Silymarin prevents acetaminophen induced hepatotoxicity via up regulation of the glutathione conjugation capacity in mice ScienceDirect