Central and Peripheral Molecular Targets for Antiobesity Pharmacotherapy Doing everything right but that last layer won't move? It's not discipline. It's biology. Some fat stores are built to resist breakdown. That's why you plateauno matter how hard you push. AOD 9604 The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver ScienceDirect Adipocyte Differentiation, Pluripotency and Molecular Mechanisms Frontiers Research Topic AOD 9604 targets the fat signaling region of growth hormone, activating lipolysis while leaving insulin and IGF 1 unchanged. Growth hormone regulates fat metabolism through a specific domain in its molecular structure, the amino acids AOD9604 IASP International