Methimazole induced hypothyroidism causes alteration of the REDOX environment, oxidative stress, and hepatic damage; events not caused by hypothyroidism itself Annals of Hepatology Metabolic Characteristics of Hashimoto's Thyroiditis Patients and the Role of Microelements and Diet in the Disease ManagementAn Overview Frontiers Selenium and thyroid diseases OXIDATIVE STRESScan contribute to hypothyroid symptoms When the body has to deal with too much Oxidative Stress from inflammation, then the enzyme Glutathione Peroxidase [GPx] has to work overtime to inactivate damaging " A Comprehensive Review of Selenium as a Key Regulator in Thyroid Health Biological Trace Element Research Springer Nature Link Oxidative stress in Hashimoto's thyroiditis: possible adjuvant therapies to attenuate deleterious effects Molecular and Cellular Biochemistry Springer Nature Link